Peptidyl amidating enzyme Sextexting chat
The inactive precursor protein is progressively hydrolyzed into smaller fragments (one of which is neurophysin I) via a series of enzymes.The last hydrolysis that releases the active oxytocin nonapeptide is catalyzed by peptidylglycine alpha-amidating monooxygenase (PAM).One theory states that oxytocin increases approach/avoidance to certain social stimuli and the second theory states that oxytocin increases the salience of certain social stimuli, causing the animal or human to pay closer attention to socially relevant stimuli.Facial expressions of disgust are evolutionarily linked to the idea of contagion.Oxytocin enhances the aversive social memory, leading the rat to display a greater fear response when the aversive stimulus is encountered again.It has been shown that oxytocin differentially affects males and females.
By chance, sodium ascorbate by itself was found to stimulate the production of oxytocin from ovarian tissue over a range of concentrations in a dose-dependent manner.
Oxytocin has peripheral (hormonal) actions, and also has actions in the brain.
Its actions are mediated by specific, oxytocin receptors.
Consequently, oxytocin is often referred to as the “love hormone".
Two dominant theories explain the role of oxytocin in fear and anxiety.The peripheral actions of oxytocin mainly reflect secretion from the pituitary gland.